SNAP23
synaptosomal-associated protein, 23kDa
Sinónimos:
HsT17016, SNAP-23, SNAP23A, SNAP23B
Especie:
Human SNAP23 (8773), Mouse Snap23 (20619), Rat Snap23 (64630), cow SNAP23 (522423), chicken SNAP23 (423235), domestic cat SNAP23 (101101473), sheep SNAP23 (101117588), domestic guinea pig Snap23 (100722747), naked mole-rat Snap23 (101711373), dog SNAP23 (478268)
ID UniProtKB:
ID del gen:
- Human(8773) Summary: Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- Mouse(20619) synaptosomal-associated protein 23
- Rat(64630) synaptosomal-associated protein 23
- cow(522423) synaptosomal-associated protein, 23kDa
- chicken(423235) synaptosomal-associated protein, 23kDa
- domestic cat(101101473) synaptosomal-associated protein, 23kDa
- sheep(101117588) synaptosomal-associated protein, 23kDa
- domestic guinea pig(100722747) synaptosomal-associated protein, 23kDa
- naked mole-rat(101711373) synaptosomal-associated protein, 23kDa
- dog(478268) synaptosomal-associated protein, 23kDa
- Domestic Rabbit(100008776) synaptosomal-associated protein, 23kDa
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