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Merck

STAT1

signal transducer and activator of transcription 1, 91kDa

Sinónimos:
CANDF7, ISGF-3, STAT91
Especie:
ID UniProtKB:
ID del gen:
  • Human(6772) Summary: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(20846) signal transducer and activator of transcription 1
  • Rat(25124) signal transducer and activator of transcription 1
  • dog(488449) signal transducer and activator of transcription 1, 91kDa
  • sheep(100307049) signal transducer and activator of transcription 1, 91kDa
  • cow(510814) signal transducer and activator of transcription 1, 91kDa
  • Domestic Rabbit(100343893) signal transducer and activator of transcription 1, 91kDa
  • domestic guinea pig(100724708) signal transducer and activator of transcription 1, 91kDa
  • naked mole-rat(101718902) signal transducer and activator of transcription 1, 91kDa
  • chicken(424044) signal transducer and activator of transcription 1, 91kDa

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-STAT1 Antibody, CT, Upstate®, from rabbit,
Reactividad de especies
human, mouse
Aplicación
electrophoretic mobility shift assay
immunoprecipitation (IP)

western blot
Anti-STAT1 (isoform alpha) Antibody, clone 1D4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-phospho-STAT1 (Tyr701) Antibody, Upstate®, from rabbit,
Reactividad de especies
chicken, human, mouse, rat
Aplicación
western blot
Anti-STAT1-α Antibody, Chemicon®, from rabbit,
Reactividad de especies
human, mouse
Aplicación
immunoprecipitation (IP)
western blot
Anti-Phospho-STAT1-Y701 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

Proteins

Número de producto
Descripción
Especie
STAT1 human, recombinant, expressed in insect cells, ≥70% (SDS-PAGE),
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Stat1,
Especie
mouse
MISSION® esiRNA, targeting human STAT1,
Especie
human