TP63
tumor protein p63
Sinónimos:
AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L
Especie:
Human TP63 (8626), Rat Tp63 (246334), Zebrafish tp63 (260407), chicken TP63 (374269), dog TP63 (488125), domestic cat TP63 (101095124), domestic guinea pig Tp63 (100732143), Horse TP63 (100059752), sheep TP63 (101108874), sheep TP63 (100048992) ...Más
ID UniProtKB:
ID del gen:
- Human(8626) Summary: This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008]
- Rat(246334) tumor protein p63
- Zebrafish(260407) tumor protein p63
- chicken(374269) tumor protein p63
- dog(488125) tumor protein p63
- domestic cat(101095124) tumor protein p63
- domestic guinea pig(100732143) tumor protein p63
- Horse(100059752) tumor protein p63
- sheep(101108874) tumor protein p63
- sheep(100048992) tumor protein p63
- naked mole-rat(101710600) tumor protein p63
- cow(615335) tumor protein p63
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-p40 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot
western blot
Anti-p63 (Tumor Protein 63) Rabbit Monoclonal Antibody, clone RM383, affinity purified immunoglobulin,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-P40 (TP63) Antibody, clone 11H1, clone 11H1, from mouse,
Reactividad de especies
human
Aplicación
western blot
Anti-p40 (deltaNp63) Rabbit Monoclonal Antibody, clone RM392, affinity purified immunoglobulin,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-P40 Antibody, clone 11F12.1, clone 11F12.1, from mouse,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
esiRNA
Número de producto
Descripción
Especie