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Merck

74875

8-Octanoyloxypyrene-1,3,6-trisulfonic acid trisodium salt

suitable for fluorescence, ≥90% (HPCE)

Sinónimos:

Trisodium 8-octanoyloxypyrene-1,3,6-trisulfonate

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25 MG
US$ 520,00

US$ 520,00

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Fórmula empírica (notación de Hill):
C24H21Na3O11S3
Número CAS:
Peso molecular:
650.58
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.32

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Quality Level

assay

≥90% (HPCE)

form

powder

mp

251-260 °C (lit.)

solubility

DMF: soluble
DMSO: soluble
H2O: soluble
methanol: soluble

fluorescence

λex 384 nm; λem 409 nm in H2O
λex 460 nm; λem 510 nm in 0.1 M Tris pH 8.0 (esterase)

suitability

suitable for fluorescence

storage temp.

−20°C

SMILES string

[Na+].[Na+].[Na+].CCCCCCCC(=O)Oc1cc(c2ccc3c(cc(c4ccc1c2c34)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O

InChI

1S/C24H24O11S3.3Na/c1-2-3-4-5-6-7-22(25)35-18-12-19(36(26,27)28)15-10-11-17-21(38(32,33)34)13-20(37(29,30)31)16-9-8-14(18)23(15)24(16)17;;;/h8-13H,2-7H2,1H3,(H,26,27,28)(H,29,30,31)(H,32,33,34);;;/q;3*+1/p-3

InChI key

RZVSWISDVXUSGY-UHFFFAOYSA-K

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Este artículo
A7222H152946935
assay

≥90% (HPCE)

assay

≥96.0% (HPCE)

assay

≥96%

assay

≥90% (HPCE)

suitability

suitable for fluorescence

suitability

-

suitability

-

suitability

suitable for fluorescence

solubility

DMF: soluble, H2O: soluble, DMSO: soluble, methanol: soluble

solubility

-

solubility

-

solubility

DMF: soluble, DMSO: soluble

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

200

form

powder

form

solid

form

-

form

solid

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

Application

suitable as fluorogenic substrate for esterases, lipases

Other Notes

Highly water soluble enzyme substrate for fluorimetric assay of esterases and lipases at longwave excitation and emission wavelengths[1]

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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O S Wolfbeis et al.
Analytical biochemistry, 129(2), 365-370 (1983-03-01)
A direct and continuous kinetic method for the fluorimetric assay of various hydrolases by using new, highly water-soluble substrates is described. The latter consist of esters of strongly fluorescent 1-hydroxypyren-3,6,8-trisulfonic acid trisodium salt with acetic, butyric, caprylic, and oleic acid.
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Our collaborative successful gene replacement therapy using AAV vectors expressing a variant of human RPGR-ORF15 in two canine models provided therapeutic proof of concept for translation into human treatment. The ORF15 sequence contained within this AAV vector, however, has ORF15
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Nature communications, 6, 8623-8623 (2015-10-16)
Phagocytosis is responsible for the elimination of particles of widely disparate sizes, from large fungi or effete cells to small bacteria. Though superficially similar, the molecular mechanisms involved differ: engulfment of large targets requires phosphoinositide 3-kinase (PI3K), while that of

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