API5
apoptosis inhibitor 5
Synonyme:
AAC-11, AAC11
Spezies:
Human API5 (8539), Mouse Api5 (11800), Rat Api5 (362170), Zebrafish api5 (321676), Horse API5 (100050009), domestic guinea pig Api5 (100717249), naked mole-rat Api5 (101719611), sheep API5 (101108774), Domestic Rabbit API5 (100345733), cow API5 (538968) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(8539) Summary: This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
- Mouse(11800) apoptosis inhibitor 5
- Rat(362170) apoptosis inhibitor 5
- Zebrafish(321676) apoptosis inhibitor 5
- Horse(100050009) apoptosis inhibitor 5
- domestic guinea pig(100717249) apoptosis inhibitor 5
- naked mole-rat(101719611) apoptosis inhibitor 5
- sheep(101108774) apoptosis inhibitor 5
- Domestic Rabbit(100345733) apoptosis inhibitor 5
- cow(538968) apoptosis inhibitor 5
- domestic cat(101081754) apoptosis inhibitor 5
- dog(483413) apoptosis inhibitor 5
- chicken(423168) apoptosis inhibitor 5
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