ATF1
activating transcription factor 1
Synonyme:
EWS-ATF1, FUS/ATF-1, TREB36
Spezies:
Human ATF1 (466), Mouse Atf1 (11908), Rat Atf1 (315305), naked mole-rat Atf1 (101726719), cow ATF1 (506967), sheep ATF1 (101117917), domestic cat ATF1 (101088253), Zebrafish atf1 (325609), chicken ATF1 (426873), domestic guinea pig Atf1 (100719533)
UniProtKB-ID:
Gen-ID:
- Human(466) Summary: This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. [provided by RefSeq, Aug 2010]
- Mouse(11908) activating transcription factor 1
- Rat(315305) activating transcription factor 1
- naked mole-rat(101726719) activating transcription factor 1
- cow(506967) activating transcription factor 1
- sheep(101117917) activating transcription factor 1
- domestic cat(101088253) activating transcription factor 1
- Zebrafish(325609) activating transcription factor 1
- chicken(426873) activating transcription factor 1
- domestic guinea pig(100719533) activating transcription factor 1
- dog(486545) activating transcription factor 1
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-ATF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ATF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
ChIP
immunofluorescence
immunofluorescence
Anti-ATF1 Antibody, clone 1N21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human
Anwendung
affinity binding assay
immunocytochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunoprecipitation (IP)
western blot