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BCAR3

breast cancer anti-estrogen resistance 3

Synonyme:
NSP2, SH2D3B
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(8412) Summary: Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
  • Mouse(29815) breast cancer anti-estrogen resistance 3
  • Rat(310838) breast cancer anti-estrogen resistance 3
  • Zebrafish(570610) breast cancer anti-estrogen resistance 3
  • chicken(424494) breast cancer anti-estrogen resistance 3
  • Domestic Rabbit(100352424) breast cancer anti-estrogen resistance 3
  • cow(506231) breast cancer anti-estrogen resistance 3
  • sheep(101106808) breast cancer anti-estrogen resistance 3
  • domestic cat(101099315) breast cancer anti-estrogen resistance 3
  • domestic guinea pig(100717989) breast cancer anti-estrogen resistance 3
  • Horse(100059015) breast cancer anti-estrogen resistance 3
  • naked mole-rat(101704053) breast cancer anti-estrogen resistance 3
  • dog(479941) breast cancer anti-estrogen resistance 3

Custom & Knockdown Gene Products

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-BCAR3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-BCAR3 Antibody, from rabbit, purified by affinity chromatography,
Speziesreaktivität
human, mouse
Anwendung
western blot
Anti-BCAR3 Antibody, clone 9D9.1, clone 9D9.1, from mouse,
Speziesreaktivität
human
Anwendung
western blot
Rabbit anti-BCAR3 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Speziesreaktivität
human
Anwendung
immunoprecipitation (IP)
western blot
Anti-BCAR3 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
canine, human, pig
Anwendung
ELISA
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Bcar3,
Spezies
mouse
MISSION® esiRNA, targeting human BCAR3,
Spezies
human