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BMPR1B

bone morphogenetic protein receptor, type IB

Synonyme:
ALK-6, ALK6, CDw293
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(658) Summary: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
  • Mouse(12167) bone morphogenetic protein receptor, type 1B
  • Rat(310914) bone morphogenetic protein receptor, type IB
  • sheep(443454) bone morphogenetic protein receptor, type IB
  • dog(478484) bone morphogenetic protein receptor, type IB
  • domestic guinea pig(100732675) bone morphogenetic protein receptor, type IB
  • naked mole-rat(101710196) bone morphogenetic protein receptor, type IB
  • Domestic Rabbit(100351275) bone morphogenetic protein receptor, type IB
  • domestic cat(101082489) bone morphogenetic protein receptor, type IB
  • chicken(396030) bone morphogenetic protein receptor, type IB
  • cow(407128) bone morphogenetic protein receptor, type IB

Custom & Knockdown Gene Products

ELISA

Produktnummer
Beschreibung
Spezies
Human ALK-6 ELISA, for serum, plasma and cell culture supernatants,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-BMPR1B antibody produced in mouse, clone 2F3, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
Monoclonal Anti-BMPR1B antibody produced in mouse, clone 2E2, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, mouse
Anwendung
ELISA
western blot