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CD74

CD74 molecule, major histocompatibility complex, class II invariant chain

Synonyme:
DHLAG, HLADG, II, Ia-GAMMA
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(972) Summary: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
  • Mouse(16149) CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
  • Rat(25599) Cd74 molecule, major histocompatibility complex, class II invariant chain
  • cow(613384) CD74 molecule, major histocompatibility complex, class II invariant chain
  • domestic cat(101085953) CD74 molecule, major histocompatibility complex, class II invariant chain
  • domestic guinea pig(100735496) CD74 molecule, major histocompatibility complex, class II invariant chain
  • dog(479329) CD74 molecule, major histocompatibility complex, class II invariant chain
  • sheep(101102561) CD74 molecule, major histocompatibility complex, class II invariant chain
  • chicken(414741) CD74 molecule, major histocompatibility complex, class II invariant chain
  • naked mole-rat(101723625) CD74 molecule, major histocompatibility complex, class II invariant chain

Custom & Knockdown Gene Products

ELISA

Produktnummer
Beschreibung
Spezies
Human CD74 ELISA, for serum, plasma and cell culture supernatants,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CD74 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-MHC-Klasse II (I-A/I-E) Antikörper, Klon M5/114, clone M5/114, from rat,
Speziesreaktivität
mouse
Anwendung
flow cytometry
immunohistochemistry

western blot
Anti-MHC class II (I-A/I-E), redFluor® 710, clone M5/114 .15.2 Antibody, clone M5/114.15.2, from rat, redFluor® 710,
Speziesreaktivität
mouse
Anwendung
flow cytometry
Anti-MHC class II (I-A/I-E), violetFluor® 450, clone M5/114 .15.2 Antibody, clone M5/114.15.2, from rat, violetFluor® 450,
Speziesreaktivität
mouse
Anwendung
flow cytometry
Monoclonal Anti-CD74 antibody produced in mouse, clone 3D7,
Speziesreaktivität
human
Anwendung
flow cytometry
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Cd74,
Spezies
mouse
MISSION® esiRNA, targeting human CD74,
Spezies
human