CDC27
cell division cycle 27
Synonyme:
ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, HNUC, NUC2
Spezies:
Human CDC27 (996), Mouse Cdc27 (217232), Rat Cdc27 (360643), naked mole-rat Cdc27 (101717421), domestic cat CDC27 (101091234), fruit fly Cdc27 (38798), dog CDC27 (490924), chicken CDC27 (419960), cow CDC27 (540660), domestic guinea pig Cdc27 (100731091) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(996) Summary: The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(217232) cell division cycle 27
- Rat(360643) cell division cycle 27
- naked mole-rat(101717421) cell division cycle 27
- domestic cat(101091234) cell division cycle 27 homolog (S. cerevisiae)
- fruit fly(38798) CG8610 gene product from transcript CG8610-RB
- dog(490924) cell division cycle 27 homolog (S. cerevisiae)
- chicken(419960) cell division cycle 27 homolog (S. cerevisiae)
- cow(540660) cell division cycle 27 homolog (S. cerevisiae)
- domestic guinea pig(100731091) cell division cycle 27
- Zebrafish(30450) cell division cycle 27
- Horse(100054552) cell division cycle 27 homolog (S. cerevisiae)
- sheep(101121276) cell division cycle 27 homolog (S. cerevisiae)
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CDC27 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
Anti-CDC27 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Cdc27 antibody,Mouse monoclonal, clone AF3.1, purified from hybridoma cell culture,
Speziesreaktivität
xenopus, bovine, canine, human, mouse, rat
Anwendung
ELISA
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot