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CDH1

cadherin 1, type 1, E-cadherin (epithelial)

Synonyme:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
  • Mouse(12550) cadherin 1
  • Rat(83502) cadherin 1
  • dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
  • chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
  • naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
  • Zebrafish(114424) cadherin 1, epithelial
  • cow(282637) cadherin 1, type 1, E-cadherin (epithelial)

Custom & Knockdown Gene Products

ELISA

Produktnummer
Beschreibung
Spezies
Mouse E-Cadherin ELISA Kit, for serum, plasma and cell culture supernatant,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-E-Cadherin Antibody, serum, Upstate®,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-E-cadherin antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-E-Cadherin antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-E-Cadherin Antibody, clone 67A4, Azide Free, clone 67A4, Chemicon®, from mouse,
Speziesreaktivität
human
Anwendung
flow cytometry
immunofluorescence
Anti-E-Cadherin/CD324 Antibody, clone 19A11, ,
Speziesreaktivität
canine, human
Anwendung
ELISA
immunocytochemistry

inhibition assay

western blot

Cell Lines

Produktnummer
Beschreibung
Spezies
MCF10A CELLS CDH1 (-/-), ,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
E-Cadherin human, recombinant, expressed in E. coli, 0.5 mg protein/mL,
Spezies
human
E-Cadherin/Fc Chimera from mouse, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Spezies
mouse

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human CDH1,
Spezies
human
MISSION® esiRNA, targeting mouse Cdh1,
Spezies
mouse