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CDH5

cadherin 5, type 2 (vascular endothelium)

Synonyme:
7B4, CD144
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(1003) Summary: This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(12562) cadherin 5
  • Rat(307618) cadherin 5
  • naked mole-rat(101706580) cadherin 5, type 2 (vascular endothelium)
  • domestic guinea pig(100727685) cadherin 5, type 2 (vascular endothelium)
  • sheep(101107462) cadherin 5, type 2 (vascular endothelium)
  • Domestic Rabbit(100301529) cadherin 5, type 2 (vascular endothelium)
  • chicken(374068) cadherin 5, type 2 (vascular endothelium)
  • domestic cat(101084501) cadherin 5, type 2 (vascular endothelium)
  • cow(414735) cadherin 5, type 2 (vascular endothelium)
  • dog(489775) cadherin 5, type 2 (vascular endothelium)
  • Zebrafish(445471) cadherin 5

Custom & Knockdown Gene Products

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-VE-cadherin Antibody, clone BV6, clone BV6, from mouse,
Speziesreaktivität
human
Anwendung
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-VE-Cadherin-Antikörper (CD144), Klon BV9, clone BV9, from mouse,
Speziesreaktivität
human
Anwendung
activity assay
immunocytochemistry
Anti-VE-Cadherin (CD144) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-CDH5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
western blot
Anti-phospho-VE-cadherin (Tyr731), from rabbit, purified by affinity chromatography,
Speziesreaktivität
human, mouse
Anwendung
inhibition assay
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Cdh5,
Spezies
mouse
MISSION® esiRNA, targeting human CDH5,
Spezies
human