CLDN18
claudin 18
Synonyme:
SFTA5, SFTPJ
Spezies:
Human CLDN18 (51208), Mouse Cldn18 (56492), Rat Cldn18 (315953), naked mole-rat Cldn18 (101705422), cow CLDN18 (511460), domestic guinea pig Cldn18 (100730947), chicken CLDN18 (429135), dog CLDN18 (477079), sheep CLDN18 (101112106), domestic cat CLDN18 (101093797)
UniProtKB-ID:
Gen-ID:
- Human(51208) Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010]
- Mouse(56492) claudin 18
- Rat(315953) claudin 18
- naked mole-rat(101705422) claudin 18
- cow(511460) claudin 18
- domestic guinea pig(100730947) claudin 18
- chicken(429135) claudin 18
- dog(477079) claudin 18
- sheep(101112106) claudin 18
- domestic cat(101093797) claudin 18
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CLDN18 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-Claudin-18 Antibody, clone 1G17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, rat
Anwendung
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CLDN18, affinity isolated antibody,
Speziesreaktivität
horse, human, mouse, rat
Anwendung
western blot
esiRNA
Produktnummer
Beschreibung
Spezies