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CTSL

cathepsin L

Synonyme:
CATL, CTSL1, MEP
Spezies:
Human CTSL (1514), Mouse Ctsl (13039)
UniProtKB-ID:
Gen-ID:
  • Human(1514) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]
  • Mouse(13039) cathepsin L

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ELISA

Produktnummer
Beschreibung
Spezies
RAB0635
Human CTSL / Cathepsin L1 ELISA Kit, ,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
HPA070413
Anti-CTSL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
western blot
SAB4300959
Anti-CTSL antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse
Anwendung
immunohistochemistry
western blot
C2970
Monoclonal Anti-Cathepsin L antibody produced in mouse, clone 33/2, ascites fluid,
Speziesreaktivität
human, mink, mouse, rat
Anwendung
ELISA
immunohistochemistry
microarray
western blot

Proteins

Produktnummer
Beschreibung
Spezies
219402
Cathepsin L, humane Leber, Cathepsin L, Human Liver, CAS 60616-82-2, is a native, the most potent of all the lysosomal proteinases. Plays a major role in the proteolysis of both cellular and endocytosed macromolecules.,
Spezies
human
SRP0291
Cathepsin L Active human, recombinant, expressed in FreeStyle™ 293-F cells, ≥90% (SDS-PAGE),
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
EHU106791
MISSION® esiRNA, targeting human CTSL,
Spezies
human