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Merck

CYBB

cytochrome b-245, beta polypeptide

Synonyme:
AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX
Spezies:
Human CYBB (1536), Mouse Cybb (13058), Rat Cybb (66021), cow CYBB (281112), sheep CYBB (100036757), Domestic Rabbit CYBB (100008801), dog CYBB (491825), chicken CYBB (418581), Zebrafish cybb (393386)
UniProtKB-ID:
P04839, A8K138, Q2PP16
Gen-ID:
  • Human(1536) Summary: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
  • Mouse(13058) cytochrome b-245, beta polypeptide
  • Rat(66021) cytochrome b-245, beta polypeptide
  • cow(281112) cytochrome b-245, beta polypeptide
  • sheep(100036757) cytochrome b-245, beta polypeptide
  • Domestic Rabbit(100008801) cytochrome b-245 beta polypeptide
  • dog(491825) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
  • chicken(418581) cytochrome b-245, beta polypeptide
  • Zebrafish(393386) cytochrome b-245, beta polypeptide (chronic granulomatous disease)

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
ZRB2447
Anti-NOX2/gp91phox Antibody, clone 1J16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human
Anwendung
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
MABS2195
Anti-gp91phox (NOX2) Antibody, ,
Speziesreaktivität
human
Anwendung
flow cytometry
western blot
07-024
Anti-GP91-PHOX-Antikörper, Upstate®, from rabbit,
Speziesreaktivität
human
Anwendung
western blot
MABS2193
Anti-gp91phox (NOX2) Antibody, ,
Speziesreaktivität
human
Anwendung
flow cytometry
inhibition assay
western blot
SAB4300724
Anti-CYBB antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
EHU010941
MISSION® esiRNA, targeting human CYBB,
Spezies
human