DCLK2
doublecortin-like kinase 2
Synonyme:
CL2, CLICK-II, CLICK2, CLIK2, DCAMKL2, DCDC3, DCDC3B, DCK2
Spezies:
Human DCLK2 (166614), Mouse Dclk2 (70762), Rat Dclk2 (310698), dog DCLK2 (482642), Zebrafish dclk2 (572548), chicken DCLK2 (422473), naked mole-rat Dclk2 (101709014), domestic guinea pig Dclk2 (100715349), Domestic Rabbit DCLK2 (100356475), cow DCLK2 (536110) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(166614) Summary: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Sep 2010]
- Mouse(70762) doublecortin-like kinase 2
- Rat(310698) doublecortin-like kinase 2
- dog(482642) doublecortin-like kinase 2
- Zebrafish(572548) doublecortin-like kinase 2
- chicken(422473) doublecortin-like kinase 2
- naked mole-rat(101709014) doublecortin-like kinase 2
- domestic guinea pig(100715349) doublecortin-like kinase 2
- Domestic Rabbit(100356475) doublecortin-like kinase 2
- cow(536110) doublecortin-like kinase 2
- sheep(101103094) doublecortin-like kinase 2
- Horse(100062533) doublecortin-like kinase 2
- domestic cat(101093682) doublecortin-like kinase 2
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-DCLK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-DCLK2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot