DUSP5
dual specificity phosphatase 5
Synonyme:
DUSP, HVH3
Spezies:
Human DUSP5 (1847), Mouse Dusp5 (240672), Rat Dusp5 (171109), naked mole-rat Dusp5 (101726329), domestic guinea pig Dusp5 (100729004), cow DUSP5 (507061), domestic cat DUSP5 (101098828), Domestic Rabbit DUSP5 (100343162), sheep DUSP5 (101118748), chicken DUSP5 (423890) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(1847) Summary: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq, Jul 2008]
- Mouse(240672) dual specificity phosphatase 5
- Rat(171109) dual specificity phosphatase 5
- naked mole-rat(101726329) dual specificity phosphatase 5
- domestic guinea pig(100729004) dual specificity phosphatase 5
- cow(507061) dual specificity phosphatase 5
- domestic cat(101098828) dual specificity phosphatase 5
- Domestic Rabbit(100343162) dual specificity phosphatase 5
- sheep(101118748) dual specificity phosphatase 5
- chicken(423890) dual specificity phosphatase 5
- Zebrafish(114436) dual specificity phosphatase 5
- dog(486884) dual specificity phosphatase 5
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-DUSP5 antibody produced in mouse, clone 2F3, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, rat
Anwendung
ELISA
immunofluorescence
western blot
immunofluorescence
western blot