EIF2AK3
eukaryotic translation initiation factor 2-alpha kinase 3
Synonyme:
PEK, PERK, WRS
Spezies:
Human EIF2AK3 (9451), Mouse Eif2ak3 (13666), Rat Eif2ak3 (29702), Horse EIF2AK3 (100066488), domestic cat EIF2AK3 (101095973), cow EIF2AK3 (535820), Zebrafish eif2ak3 (559564), dog EIF2AK3 (475756), chicken EIF2AK3 (422930), sheep EIF2AK3 (101110042) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(9451) Summary: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Jan 2010]
- Mouse(13666) eukaryotic translation initiation factor 2 alpha kinase 3
- Rat(29702) eukaryotic translation initiation factor 2 alpha kinase 3
- Horse(100066488) eukaryotic translation initiation factor 2-alpha kinase 3
- domestic cat(101095973) eukaryotic translation initiation factor 2-alpha kinase 3
- cow(535820) eukaryotic translation initiation factor 2-alpha kinase 3
- Zebrafish(559564) eukaryotic translation initiation factor 2-alpha kinase 3
- dog(475756) eukaryotic translation initiation factor 2-alpha kinase 3
- chicken(422930) eukaryotic translation initiation factor 2-alpha kinase 3
- sheep(101110042) eukaryotic translation initiation factor 2-alpha kinase 3
- domestic guinea pig(100725836) eukaryotic translation initiation factor 2-alpha kinase 3
- naked mole-rat(101713561) eukaryotic translation initiation factor 2-alpha kinase 3
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Phospho-PERK-T982 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot
Anti-PERK Antibody, clone 4F6.1, clone 4F6.1, from mouse,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
western blot
Anti-phospho-PEK/PERK (pThr981) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-EIF2AK3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-E2AK3 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Cell Lines
Produktnummer
Beschreibung
Spezies
Proteins
Produktnummer
Beschreibung
Spezies
EIF2AK3 (563-1115), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human