FGD4
FYVE, RhoGEF and PH domain containing 4
Synonyme:
CMT4H, FRABP, ZFYVE6
Spezies:
Human FGD4 (121512), Mouse Fgd4 (224014), Rat Fgd4 (246174), Horse FGD4 (100070016), naked mole-rat Fgd4 (101712073), cow FGD4 (505234), domestic guinea pig Fgd4 (100733109), sheep FGD4 (101105233), chicken FGD4 (418133), dog FGD4 (486615)
UniProtKB-ID:
Gen-ID:
- Human(121512) Summary: This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. [provided by RefSeq, Oct 2008]
- Mouse(224014) FYVE, RhoGEF and PH domain containing 4
- Rat(246174) FYVE, RhoGEF and PH domain containing 4
- Horse(100070016) FYVE, RhoGEF and PH domain containing 4
- naked mole-rat(101712073) FYVE, RhoGEF and PH domain containing 4
- cow(505234) FYVE, RhoGEF and PH domain containing 4
- domestic guinea pig(100733109) FYVE, RhoGEF and PH domain containing 4
- sheep(101105233) FYVE, RhoGEF and PH domain containing 4
- chicken(418133) FYVE, RhoGEF and PH domain containing 4
- dog(486615) FYVE, RhoGEF and PH domain containing 4
- domestic cat(101090877) FYVE, RhoGEF and PH domain containing 4
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-FGD4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
immunohistochemistry
esiRNA
Produktnummer
Beschreibung
Spezies