GCDH
glutaryl-CoA dehydrogenase
Synonyme:
ACAD5, GCD
Spezies:
Human GCDH (2639), Mouse Gcdh (270076), Rat Gcdh (364975), Zebrafish gcdh (393860), sheep GCDH (101122190), chicken GCDH (771098), domestic cat GCDH (101086880), dog GCDH (476696), domestic guinea pig Gcdh (100714939), cow GCDH (506310) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(2639) Summary: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. [provided by RefSeq, Mar 2013]
- Mouse(270076) glutaryl-Coenzyme A dehydrogenase
- Rat(364975) glutaryl-CoA dehydrogenase
- Zebrafish(393860) glutaryl-Coenzyme A dehydrogenase
- sheep(101122190) glutaryl-CoA dehydrogenase
- chicken(771098) glutaryl-CoA dehydrogenase
- domestic cat(101086880) glutaryl-CoA dehydrogenase
- dog(476696) glutaryl-CoA dehydrogenase
- domestic guinea pig(100714939) glutaryl-CoA dehydrogenase
- cow(506310) glutaryl-CoA dehydrogenase
- Horse(100063310) glutaryl-CoA dehydrogenase
- Domestic Rabbit(100343376) glutaryl-CoA dehydrogenase
- naked mole-rat(101718348) glutaryl-CoA dehydrogenase
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-GCDH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
western blot
Anti-GCDH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-GCDH antibody produced in rabbit, IgG fraction of antiserum,
Speziesreaktivität
dog, horse, human, mouse, pig, rabbit, rat
Anwendung
immunohistochemistry
western blot
western blot