Direkt zum Inhalt
Merck

HHIP

hedgehog interacting protein

Synonyme:
HIP
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(64399) Summary: This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.[provided by RefSeq, Feb 2011]
  • Mouse(15245) Hedgehog-interacting protein
  • Rat(291936) Hedgehog-interacting protein
  • Domestic Rabbit(100344588) hedgehog interacting protein
  • domestic cat(101087058) hedgehog interacting protein
  • sheep(101111396) hedgehog interacting protein
  • cow(540830) hedgehog interacting protein
  • chicken(422460) hedgehog interacting protein
  • Zebrafish(326102) hedgehog interacting protein
  • naked mole-rat(101724427) hedgehog interacting protein
  • dog(475452) hedgehog interacting protein
  • Horse(100062868) hedgehog interacting protein
  • domestic guinea pig(100728644) hedgehog interacting protein

Custom & Knockdown Gene Products

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-HHIP antibody produced in mouse, clone 5D11, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-HHIP antibody produced in rabbit, ,
Speziesreaktivität
chicken, human, mouse
Anwendung
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human HHIP,
Spezies
human
MISSION® esiRNA, targeting mouse Hhip,
Spezies
mouse