Direkt zum Inhalt
Merck

ISCU

iron-sulfur cluster assembly enzyme

Synonyme:
2310020H20Rik, HML, ISU2, NIFU, NIFUN, hnifU
Spezies:
Human ISCU (23479), Mouse Iscu (66383), Rat Iscu (288740), cow ISCU (514789), chicken ISCU (416891), naked mole-rat Iscu (101713201), sheep ISCU (101103093), dog ISCU (477527), domestic cat ISCU (101088192), domestic guinea pig Iscu (100724516)
UniProtKB-ID:
Q9H1K1, Q6P713, Q99617, Q9H1K2
Gen-ID:
  • Human(23479) Summary: Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. [provided by RefSeq, Jul 2008]
  • Mouse(66383) IscU iron-sulfur cluster scaffold homolog (E. coli)
  • Rat(288740) iron-sulfur cluster scaffold homolog (E. coli)
  • cow(514789) iron-sulfur cluster scaffold homolog (E. coli)
  • chicken(416891) iron-sulfur cluster scaffold homolog (E. coli)
  • naked mole-rat(101713201) iron-sulfur cluster scaffold homolog (E. coli)
  • sheep(101103093) iron-sulfur cluster scaffold homolog (E. coli)
  • dog(477527) iron-sulfur cluster scaffold homolog (E. coli)
  • domestic cat(101088192) iron-sulfur cluster scaffold homolog (E. coli)
  • domestic guinea pig(100724516) iron-sulfur cluster scaffold homolog (E. coli)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
HPA057592
Anti-ISCU antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
HPA038602
Anti-ISCU antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

esiRNA

Produktnummer
Beschreibung
Spezies
EMU178551
MISSION® esiRNA, targeting mouse Iscu,
Spezies
mouse