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ITGAM

integrin, alpha M (complement component 3 receptor 3 subunit)

Synonyme:
CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3684) Summary: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(16409) integrin alpha M
  • Rat(25021) integrin, alpha M
  • Horse(100064803) integrin, alpha M (complement component 3 receptor 3 subunit)
  • dog(489928) integrin, alpha M (complement component 3 receptor 3 subunit)
  • sheep(443217) integrin, alpha M (complement component 3 receptor 3 subunit)
  • domestic guinea pig(100135561) integrin, alpha M (complement component 3 receptor 3 subunit)
  • domestic cat(101087957) integrin, alpha M (complement component 3 receptor 3 subunit)
  • cow(407124) integrin, alpha M (complement component 3 receptor 3 subunit)
  • naked mole-rat(101719288) integrin, alpha M (complement component 3 receptor 3 subunit)
  • Domestic Rabbit(100351865) integrin, alpha M (complement component 3 receptor 3 subunit)

Custom & Knockdown Gene Products

ELISA

Produktnummer
Beschreibung
Spezies
Human Integrin alpha-M ELISA, for serum, plasma and cell culture supernatants,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Integrin αM [CD11b] Antibody, clone OX-42, clone OX-42, Chemicon®, from mouse,
Speziesreaktivität
rat
Anwendung
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Milli-Mark® Anti-CD11B-PE Antibody, clone 2LPM19c, clone 2LPM19c, Milli-Mark®, from mouse,
Speziesreaktivität
human
Anwendung
flow cytometry
Anti-Integrin αM [CD11b] Antibody, clone OX-42, FITC conjugated, clone OX-42, Chemicon®, from mouse,
Speziesreaktivität
rat
Anwendung
flow cytometry
immunohistochemistry
Anti-CD11b/CD18 Antibody, clone mAb107, clone mAb107, from mouse,
Speziesreaktivität
human, nonhuman primates
Anwendung
dot blot
flow cytometry

immunohistochemistry

inhibition assay
Monoclonal Anti-CD11b antibody produced in mouse, clone ICRF44, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
flow cytometry

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Itgam,
Spezies
mouse
MISSION® esiRNA, targeting human ITGAM,
Spezies
human