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ITGAV

integrin, alpha V

Synonyme:
CD51, MSK8, VNRA, VTNR
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • dog(488437) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • chicken(396420) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • sheep(443143) integrin, alpha V
  • Horse(100068706) integrin, alpha V

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Integrin αVβ3 Antibody, clone LM609, clone LM609, Chemicon®, from mouse,
Speziesreaktivität
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Anwendung
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)
Anti-Integrin-α-V-β-6-Antikörper, Klon 10D5, azidfrei, clone 10D5, Chemicon®, from mouse,
Speziesreaktivität
human, mouse, rat
Anwendung
flow cytometry
immunoprecipitation (IP)
Anti-Integrin αVβ5 Antibody, clone P1F6, clone P1F6, Chemicon®, from mouse,
Speziesreaktivität
chicken, human
Anwendung
flow cytometry
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)
Anti-Integrin αVβ8 Antibody, clone EM13309 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human
Anwendung
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-Integrin-alpha5-Antikörper (konservierungsmittelfrei), Klon SNAKA51, clone SNAKA51, from mouse, purified by using protein G,
Speziesreaktivität
human
Anwendung
activity assay
immunocytochemistry

western blot

Proteins

Produktnummer
Beschreibung
Spezies
Human Integrin αVβ3 Protein, Triton X-100 Formulation, ,
Spezies
human
Human Integrin αVβ3, Octyl-β-D-glucopyranoside Formulation, ,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Itgav,
Spezies
mouse
MISSION® esiRNA, targeting human ITGAV,
Spezies
human