LATS2
large tumor suppressor kinase 2
Synonyme:
KPM
Spezies:
Human LATS2 (26524), Mouse Lats2 (50523), Rat Lats2 (305922), sheep LATS2 (101117941), naked mole-rat Lats2 (101705060), Zebrafish lats2 (567674), Domestic Rabbit LATS2 (100356876), domestic guinea pig Lats2 (100725954), chicken LATS2 (418949), dog LATS2 (477343) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(26524) Summary: This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008]
- Mouse(50523) large tumor suppressor 2
- Rat(305922) large tumor suppressor 2
- sheep(101117941) LATS, large tumor suppressor, homolog 2 (Drosophila)
- naked mole-rat(101705060) large tumor suppressor kinase 2
- Zebrafish(567674) LATS, large tumor suppressor, homolog 2 (Drosophila)
- Domestic Rabbit(100356876) LATS, large tumor suppressor, homolog 2 (Drosophila)
- domestic guinea pig(100725954) large tumor suppressor kinase 2
- chicken(418949) LATS, large tumor suppressor, homolog 2 (Drosophila)
- dog(477343) LATS, large tumor suppressor, homolog 2 (Drosophila)
- Horse(100050150) LATS, large tumor suppressor, homolog 2 (Drosophila)
- domestic cat(101093824) LATS, large tumor suppressor, homolog 2 (Drosophila)
- cow(508208) large tumor suppressor kinase 2
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-LATS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-LATS2 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse
Anwendung
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-LATS2 Antibody, clone 1L5 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human
Anwendung
affinity binding assay
western blot
western blot
Anti-phospho-LATS1/2 (pThr1079/1041) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry
immunohistochemistry
Anti-phospho-LATS1-T1079/LATS2-T1041 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot
Proteins
Produktnummer
Beschreibung
Spezies
LATS2 (480-1088), GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human
esiRNA
Produktnummer
Beschreibung
Spezies