LCK
lymphocyte-specific protein tyrosine kinase
Synonyme:
LSK, YT16, p56lck, pp58lck
Spezies:
Human LCK (3932), Mouse Lck (16818), Rat Lck (313050), chicken LCK (396460), Zebrafish lck (414333), domestic cat LCK (101098805), dog LCK (478151), Domestic Rabbit LCK (100349102), sheep LCK (100216439), cow LCK (508890) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(3932) Summary: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008]
- Mouse(16818) lymphocyte protein tyrosine kinase
- Rat(313050) lymphocyte-specific protein tyrosine kinase
- chicken(396460) lymphocyte-specific protein tyrosine kinase
- Zebrafish(414333) lymphocyte-specific protein tyrosine kinase
- domestic cat(101098805) lymphocyte-specific protein tyrosine kinase
- dog(478151) lymphocyte-specific protein tyrosine kinase
- Domestic Rabbit(100349102) lymphocyte-specific protein tyrosine kinase
- sheep(100216439) lymphocyte-specific protein tyrosine kinase
- cow(508890) lymphocyte-specific protein tyrosine kinase
- Horse(100146139) lymphocyte-specific protein tyrosine kinase
- naked mole-rat(101714396) lymphocyte-specific protein tyrosine kinase
- domestic guinea pig(100728811) lymphocyte-specific protein tyrosine kinase
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ELISA
Produktnummer
Beschreibung
Spezies
Small Molecule - Antagonist
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-phospho-LCK (pTyr394) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot
Anti-phospho-LCK (pSer59) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
western blot
western blot
Anti-Phospho-LCK-Y394 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot
Anti-Lck-Antikörper, Klon 3A5, clone 3A5, Upstate®, from mouse,
Speziesreaktivität
human, mouse, rat
Anwendung
immunoprecipitation (IP)
western blot
western blot
Anti-Phospho-SRC Family-Y416 antibody produced in rabbit, ,
Speziesreaktivität
human
Anwendung
immunoprecipitation (IP)
western blot
western blot
Small Molecule - Inhibitor
Produktnummer
Beschreibung
Spezies
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
Spezies
human