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LEFTY2

left-right determination factor 2

Synonyme:
EBAF, LEFTA, LEFTYA, TGFB4
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(7044) Summary: This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2010]
  • Mouse(320202) left-right determination factor 2
  • Rat(289316) Left-right determination factor 2
  • domestic guinea pig(100736071) left-right determination factor 2
  • sheep(101111566) left-right determination factor 2
  • dog(490387) left-right determination factor 2
  • chicken(395529) left-right determination factor 2
  • cow(534018) left-right determination factor 2
  • naked mole-rat(101698055) left-right determination factor 2

Custom & Knockdown Gene Products

ELISA

Produktnummer
Beschreibung
Spezies
Human Lefty-A ELISA, for serum, plasma and cell culture supernatants,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-LEFTY2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Lefty2,
Spezies
mouse
MISSION® esiRNA, targeting human LEFTY2,
Spezies
human