MAP2K1
mitogen-activated protein kinase kinase 1
Synonyme:
CFC3, MAPKK1, MEK1, MKK1, PRKMK1
Spezies:
Human MAP2K1 (5604), Mouse Map2k1 (26395), Rat Map2k1 (170851), domestic guinea pig Map2k1 (100712888), dog MAP2K1 (478347), Horse MAP2K1 (100065996), domestic cat MAP2K1 (101081387), chicken MAP2K1 (415549), naked mole-rat Map2k1 (101715628), cow MAP2K1 (533199) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(5604) Summary: The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008]
- Mouse(26395) mitogen-activated protein kinase kinase 1
- Rat(170851) mitogen activated protein kinase kinase 1
- domestic guinea pig(100712888) mitogen-activated protein kinase kinase 1
- dog(478347) mitogen-activated protein kinase kinase 1
- Horse(100065996) mitogen-activated protein kinase kinase 1
- domestic cat(101081387) mitogen-activated protein kinase kinase 1
- chicken(415549) mitogen-activated protein kinase kinase 1
- naked mole-rat(101715628) mitogen-activated protein kinase kinase 1
- cow(533199) mitogen-activated protein kinase kinase 1
- Domestic Rabbit(100009316) mitogen-activated protein kinase kinase 1
- sheep(101123635) mitogen-activated protein kinase kinase 1
- Zebrafish(406728) mitogen-activated protein kinase kinase 1
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ELISA
Produktnummer
Beschreibung
Spezies
Phospho-Mek (pSer217 / 221) ELISA Kit, for detection of phospho-mek (pSer217 / 221) in human, mouse or rat cell and tissue lysates,
Spezies
human
Phospho-Mek (pSer217 / 221) and pan-Mek ELISA Kit, for detection of phospho-mek (pSer217 / 221) and pan-mek in human, mouse or rat cell and tissue lysates,
Spezies
human
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-MEK1-Antikörper, Upstate®, from rabbit,
Speziesreaktivität
human, mouse, rat
Anwendung
immunoprecipitation (IP)
western blot
western blot
Anti-Phospho-MEK1(Ser218/222)/MEK2 (Ser222/226)-Antikörper, Kaninchen, monoklonal, Upstate®, from rabbit,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot
Anti-phospho-MEK1 (Thr292) Antibody, Upstate®, from rabbit,
Speziesreaktivität
human, mouse
Anwendung
western blot
Monoclonal Anti-MAP2K1 antibody produced in mouse, clone 1B5, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
western blot
Anti-MEK1 Antibody, clone 6B7.1, clone 6B7.1, from mouse,
Speziesreaktivität
human
Anwendung
western blot
Small Molecule - Inhibitor
Produktnummer
Beschreibung
Spezies
U0126, U0126 is a elective inhibitor of MEK-1 and MEK-2; weak inhibitor of PKC, Raf, ERK, JNK, MEKK, MKK-3, MKK-4/SEK, MKK-6, Abl, Cdk2 and Cdk4.,
Spezies
human
Proteins
Produktnummer
Beschreibung
Spezies
MEK1-Protein, inaktiv, 50 g, Unactive, N-terminal GST & C-terminal His6-tagged, recombinant full-length human MEK1, for use in Kinase Assays.,
Spezies
human
MEK1 Protein, active, 10 µg, Active, N-terminal GST & C-terminal His6-tagged, recombinant full-length human MEK1, for use in Kinase Assays.,
Spezies
human
MEK1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
mouse