MARCH2
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
Synonyme:
MARCH-II, RNF172
Spezies:
Human MARCH2 (51257), Mouse March2 (224703), Rat March2 (362849), Zebrafish march2 (555611), domestic guinea pig March2 (100733733), domestic cat MARCH2 (101090087), cow MARCH2 (508949), dog MARCH2 (611624), naked mole-rat March2 (101720054), sheep MARCH2 (101103806)
UniProtKB-ID:
Gen-ID:
- Human(51257) Summary: MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]
- Mouse(224703) membrane-associated ring finger (C3HC4) 2
- Rat(362849) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
- Zebrafish(555611) membrane-associated ring finger (C3HC4) 2
- domestic guinea pig(100733733) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
- domestic cat(101090087) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
- cow(508949) membrane-associated ring finger (C3HC4) 2
- dog(611624) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
- naked mole-rat(101720054) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
- sheep(101103806) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
- chicken(420062) membrane-associated ring finger (C3HC4) 2
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-MARCH2 antibody produced in mouse, clone 7F3, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
western blot
esiRNA
Produktnummer
Beschreibung
Spezies