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MBD5

methyl-CpG binding domain protein 5

Synonyme:
MRD1
Spezies:
Human MBD5 (55777), Mouse Mbd5 (109241), Rat Mbd5 (311026), Domestic Rabbit MBD5 (100358608), sheep MBD5 (101121829), naked mole-rat Mbd5 (101708541), domestic guinea pig Mbd5 (100731243), cow MBD5 (541084), Thale Cress MBD5 (823811), chicken MBD5 (424308) ...Mehr
UniProtKB-ID:
Q9P267, A5HMQ4, A7E2B1, Q53SR1, Q9NUV6
Gen-ID:
  • Human(55777) Summary: This gene encodes a member of the methyl-CpG-binding domain (MBD) family. The MBD consists of about 70 residues and is the minimal region required for a methyl-CpG-binding protein binding specifically to methylated DNA. In addition to the MBD domain, this protein contains a PWWP domain (Pro-Trp-Trp-Pro motif), which consists of 100-150 amino acids and is found in numerous proteins that are involved in cell division, growth and differentiation. Mutations in this gene cause mental retardation autosomal dominant type 1. Haploinsufficiency of this gene is associated with a syndrome involving microcephaly, intellectual disabilities, severe speech impairment, and seizures. Alternatively spliced transcript variants have been found, but their full-length nature is not determined. [provided by RefSeq, Mar 2010]
  • Mouse(109241) methyl-CpG binding domain protein 5
  • Rat(311026) methyl-CpG binding domain protein 5
  • Domestic Rabbit(100358608) methyl-CpG binding domain protein 5
  • sheep(101121829) methyl-CpG binding domain protein 5
  • naked mole-rat(101708541) methyl-CpG binding domain protein 5
  • domestic guinea pig(100731243) methyl-CpG binding domain protein 5
  • cow(541084) methyl-CpG binding domain protein 5
  • Thale Cress(823811) methyl-CPG-binding domain protein 5
  • chicken(424308) methyl-CpG binding domain protein 5
  • Horse(100049894) methyl-CpG binding domain protein 5
  • domestic cat(101098244) methyl-CpG binding domain protein 5
  • dog(483910) methyl-CpG binding domain protein 5
  • Zebrafish(100009623) methyl-CpG binding domain protein 5

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
ABE1322
Anti-MBD5, from rabbit, purified by affinity chromatography,
Speziesreaktivität
human, mouse, rat
Anwendung
immunocytochemistry
immunohistochemistry
western blot
HPA035964
Anti-MBD5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
WH0055777M1
Monoclonal Anti-MBD5 antibody produced in mouse, clone 4A12-1B6, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
EHU126281
MISSION® esiRNA, targeting human MBD5,
Spezies
human