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OTX2

orthodenticle homeobox 2

Synonyme:
CPHD6, MCOPS5
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(5015) Summary: This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]
  • Mouse(18424) orthodenticle homolog 2 (Drosophila)
  • Rat(305858) orthodenticle homeobox 2
  • domestic guinea pig(100729098) orthodenticle homeobox 2
  • domestic cat(101094107) orthodenticle homeobox 2
  • naked mole-rat(101696878) orthodenticle homeobox 2
  • sheep(101114527) orthodenticle homeobox 2
  • chicken(395191) orthodenticle homeobox 2
  • cow(538953) orthodenticle homeobox 2
  • Domestic Rabbit(100009374) orthodenticle homeobox 2
  • Zebrafish(30501) orthodenticle homolog 2
  • dog(490708) orthodenticle homeobox 2

Custom & Knockdown Gene Products

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-OTX2-Antikörper, from rabbit, purified by affinity chromatography,
Speziesreaktivität
bovine, human, rat, rhesus macaque
Anwendung
immunohistochemistry
western blot
Anti-OTX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
ChIP
immunohistochemistry
Anti-OTX2 Antibody, clone 8D8.2, clone 8D8.2, from mouse,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-OTX2 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Anwendung
immunohistochemistry
western blot
Monoclonal Anti-OTX2 antibody produced in mouse, clone 1H12C4B5, ascites fluid,
Speziesreaktivität
human
Anwendung
ELISA
flow cytometry

immunofluorescence

immunohistochemistry

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human OTX2,
Spezies
human
MISSION® esiRNA, targeting mouse Otx2,
Spezies
mouse