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PBX1

pre-B-cell leukemia homeobox 1

Synonyme:
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(5087) Summary: This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
  • Mouse(18514) pre B cell leukemia homeobox 1
  • Rat(304947) pre-B-cell leukemia homeobox 1
  • cow(540688) pre-B-cell leukemia homeobox 1
  • domestic guinea pig(100723723) pre-B-cell leukemia homeobox 1
  • naked mole-rat(101714961) pre-B-cell leukemia homeobox 1
  • domestic cat(101081781) pre-B-cell leukemia homeobox 1
  • Horse(100058426) pre-B-cell leukemia homeobox 1
  • sheep(101108880) pre-B-cell leukemia homeobox 1
  • dog(488669) pre-B-cell leukemia homeobox 1
  • Domestic Rabbit(100341186) pre-B-cell leukemia homeobox 1
  • chicken(395505) pre-B-cell leukemia homeobox 1

Custom & Knockdown Gene Products

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-PBX1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
ChIP
immunofluorescence

immunohistochemistry

western blot
Anti-PBX1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human PBX1,
Spezies
human
MISSION® esiRNA, targeting mouse Pbx1,
Spezies
mouse