PDCD6IP
programmed cell death 6 interacting protein
Synonyme:
AIP1, ALIX, DRIP4, HP95
Spezies:
Human PDCD6IP (10015), Mouse Pdcd6ip (18571), Rat Pdcd6ip (501083), naked mole-rat Pdcd6ip (101711093), dog PDCD6IP (477015), chicken PDCD6IP (420725), Zebrafish pdcd6ip (406669), sheep PDCD6IP (101113964), cow PDCD6IP (533406), Horse PDCD6IP (100050741) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(10015) Summary: This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012]
- Mouse(18571) programmed cell death 6 interacting protein
- Rat(501083) programmed cell death 6 interacting protein
- naked mole-rat(101711093) programmed cell death 6 interacting protein
- dog(477015) programmed cell death 6 interacting protein
- chicken(420725) programmed cell death 6 interacting protein
- Zebrafish(406669) programmed cell death 6 interacting protein
- sheep(101113964) programmed cell death 6 interacting protein
- cow(533406) programmed cell death 6 interacting protein
- Horse(100050741) programmed cell death 6 interacting protein
- domestic cat(101095279) programmed cell death 6 interacting protein
- domestic guinea pig(100720447) programmed cell death 6 interacting protein
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-ALIX/PDCD6IP Antibody, clone 1D11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
bovine, canine, human, monkey, mouse, porcine
Anwendung
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-ALIX/PDCD6IP antibody produced in mouse, clone ALIX-1, purified from hybridoma cell culture,
Speziesreaktivität
human
Anwendung
flow cytometry
immunofluorescence
immunoprecipitation (IP)
western blot
immunofluorescence
immunoprecipitation (IP)
western blot
Anti-AIP1/Alix-Antikörper, from rabbit, purified by affinity chromatography,
Speziesreaktivität
human, mouse, rat
Anwendung
immunocytochemistry
western blot
western blot
Anti-Alix/Xp95 Antibody, clone 1A3, clone 1A3, from mouse,
Speziesreaktivität
xenopus, human, mouse
Anwendung
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-ALIX, from rabbit, purified by affinity chromatography,
Speziesreaktivität
human, mouse
Anwendung
immunocytochemistry
western blot
western blot