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Merck

PDE1A

phosphodiesterase 1A, calmodulin-dependent

Synonyme:
CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A
Spezies:
Human PDE1A (5136), Mouse Pde1a (18573), Rat Pde1a (81529), chicken PDE1A (424116), Zebrafish pde1a (564465), domestic cat PDE1A (101083101), dog PDE1A (403652), naked mole-rat Pde1a (101712147), sheep PDE1A (101119369), Domestic Rabbit PDE1A (100346878) ...Mehr
UniProtKB-ID:
P54750, D3DPG5, Q86VZ0, Q9C0K8, Q9C0K9, Q9C0L0, Q9C0L1, Q9C0L2
Gen-ID:
  • Human(5136) Summary: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]
  • Mouse(18573) phosphodiesterase 1A, calmodulin-dependent
  • Rat(81529) phosphodiesterase 1A, calmodulin-dependent
  • chicken(424116) phosphodiesterase 1A, calmodulin-dependent
  • Zebrafish(564465) phosphodiesterase 1A, calmodulin-dependent
  • domestic cat(101083101) phosphodiesterase 1A, calmodulin-dependent
  • dog(403652) phosphodiesterase 1A, calmodulin-dependent
  • naked mole-rat(101712147) phosphodiesterase 1A, calmodulin-dependent
  • sheep(101119369) phosphodiesterase 1A, calmodulin-dependent
  • Domestic Rabbit(100346878) phosphodiesterase 1A, calmodulin-dependent
  • cow(281969) phosphodiesterase 1A, calmodulin-dependent
  • Horse(100054082) phosphodiesterase 1A, calmodulin-dependent
  • domestic guinea pig(100527956) phosphodiesterase 1A, calmodulin-dependent

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
HPA022151
Anti-PDE1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
M2547
8-Methoxymethyl-3-isobutyl-1-methylxanthine, ≥98%,
Spezies
human
V6383
Vinpocetin, ≥98%, solid,
Spezies
human
1220506
Dipyridamol, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Y0000802
Dipyridamol für die Peakidentifizierung, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
D2850000
Dipyridamol, European Pharmacopoeia (EP) Reference Standard,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
EHU074801
MISSION® esiRNA, targeting human PDE1A,
Spezies
human
EMU077501
MISSION® esiRNA, targeting mouse Pde1a,
Spezies
mouse