PICALM
phosphatidylinositol binding clathrin assembly protein
Synonyme:
CALM, CLTH, LAP
Spezies:
Human PICALM (8301), Mouse Picalm (233489), Rat Picalm (89816), naked mole-rat Picalm (101706016), sheep PICALM (101103193), chicken PICALM (425991), domestic cat PICALM (101094948), Horse PICALM (100050701), cow PICALM (513579), domestic guinea pig Picalm (100729067)
UniProtKB-ID:
Gen-ID:
- Human(8301) Summary: This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10;11)(p13;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
- Mouse(233489) phosphatidylinositol binding clathrin assembly protein
- Rat(89816) phosphatidylinositol binding clathrin assembly protein
- naked mole-rat(101706016) phosphatidylinositol binding clathrin assembly protein
- sheep(101103193) phosphatidylinositol binding clathrin assembly protein
- chicken(425991) phosphatidylinositol binding clathrin assembly protein
- domestic cat(101094948) phosphatidylinositol binding clathrin assembly protein
- Horse(100050701) phosphatidylinositol binding clathrin assembly protein
- cow(513579) phosphatidylinositol binding clathrin assembly protein
- domestic guinea pig(100729067) phosphatidylinositol binding clathrin assembly protein
- dog(476780) phosphatidylinositol binding clathrin assembly protein
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-PICALM antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
western blot
Anti-PICALM antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PICALM, from rabbit, purified by affinity chromatography,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
western blot