PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
Synonyme:
CADP44, P44, SUG2, p42
Spezies:
Human PSMC6 (5706), Mouse Psmc6 (67089), Rat Psmc6 (289990), chicken PSMC6 (423586), dog PSMC6 (478522), domestic cat PSMC6 (101098797), cow PSMC6 (518637), Zebrafish psmc6 (321585), domestic guinea pig Psmc6 (100732212), naked mole-rat Psmc6 (101716297) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(5706) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12. [provided by RefSeq, Jul 2008]
- Mouse(67089) proteasome (prosome, macropain) 26S subunit, ATPase, 6
- Rat(289990) proteasome (prosome, macropain) 26S subunit, ATPase, 6
- chicken(423586) proteasome (prosome, macropain) 26S subunit, ATPase, 6
- dog(478522) proteasome (prosome, macropain) 26S subunit, ATPase, 6
- domestic cat(101098797) proteasome (prosome, macropain) 26S subunit, ATPase, 6
- cow(518637) proteasome (prosome, macropain) 26S subunit, ATPase, 6
- Zebrafish(321585) proteasome (prosome, macropain) 26S subunit, ATPase, 6
- domestic guinea pig(100732212) proteasome (prosome, macropain) 26S subunit, ATPase, 6
- naked mole-rat(101716297) proteasome (prosome, macropain) 26S subunit, ATPase, 6
- sheep(101116401) proteasome (prosome, macropain) 26S subunit, ATPase, 6
- Domestic Rabbit(100353955) proteasome (prosome, macropain) 26S subunit, ATPase, 6
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-PSMC6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot