PSMD8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
Synonyme:
HIP6, HYPF, Nin1p, Rpn12, S14, p31
Spezies:
Human PSMD8 (5714), Mouse Psmd8 (57296), Rat Psmd8 (292766), dog PSMD8 (476470), Zebrafish psmd8 (415221), naked mole-rat Psmd8 (101706427), domestic guinea pig Psmd8 (100731823), sheep PSMD8 (101111572), domestic cat PSMD8 (101095457), cow PSMD8 (512891)
UniProtKB-ID:
Gen-ID:
- Human(5714) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008]
- Mouse(57296) proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
- Rat(292766) proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
- dog(476470) proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
- Zebrafish(415221) proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
- naked mole-rat(101706427) proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
- domestic guinea pig(100731823) proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
- sheep(101111572) proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
- domestic cat(101095457) proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
- cow(512891) proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
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Antibodies
Produktnummer
Beschreibung
SpeziesreaktivitÀt
Anwendung
Anti-PSMD8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
SpeziesreaktivitÀt
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot