PSPN
persephin
Synonyme:
PSP
Spezies:
Human PSPN (5623), Mouse Pspn (19197), Rat Pspn (25525), cow PSPN (518266), sheep PSPN (101109705), domestic cat PSPN (101085955), dog PSPN (611734), domestic guinea pig Pspn (100717500)
UniProtKB-ID:
Gen-ID:
- Human(5623) Summary: The protein encoded by this gene is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the nervous system. These factors promote neuronal survival and can prevent the neuronal degeneration associated with injury, toxin exposure, or neurodegenerative disease. The encoded protein has amino acid similarity to its other family members, glial cell line-derived neurotrophic factor and neurturin. This gene product promotes the survival of ventral midbrain dopaminergic neurons in culture and prevents their degeneration after 6-hydroxydopamine treatment in vivo. [provided by RefSeq, Jul 2008]
- Mouse(19197) persephin
- Rat(25525) persephin
- cow(518266) persephin
- sheep(101109705) persephin
- domestic cat(101085955) persephin
- dog(611734) persephin
- domestic guinea pig(100717500) persephin
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