PTCH1
patched 1
Synonyme:
BCNS, HPE7, NBCCS, PTC, PTC1, PTCH, PTCH11
Spezies:
Human PTCH1 (5727), Mouse Ptch1 (19206), Rat Ptch1 (89830), cow PTCH1 (520994), sheep PTCH1 (101112193), Domestic Rabbit PTCH1 (100345046), domestic guinea pig Ptch1 (100729719), Horse PTCH1 (100033936), Zebrafish ptch1 (30189), chicken PTCH1 (395806) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(5727) Summary: This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq, Jul 2008]
- Mouse(19206) patched homolog 1
- Rat(89830) patched 1
- cow(520994) patched 1
- sheep(101112193) patched 1
- Domestic Rabbit(100345046) patched 1
- domestic guinea pig(100729719) patched 1
- Horse(100033936) patched 1
- Zebrafish(30189) patched 1
- chicken(395806) patched 1
- dog(484137) patched 1
- domestic cat(101085077) patched 1
- naked mole-rat(101711146) patched 1
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-PTCH1 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, dog, guinea pig, horse, human, mouse, rat
Anwendung
immunohistochemistry
western blot
western blot
Anti-PTCH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
Monoclonal Anti-PTCH antibody produced in mouse, clone 8E1, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
western blot
Anti-Patch1 antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
western blot