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Merck

PTPRA

protein tyrosine phosphatase, receptor type, A

Synonyme:
HEPTP, HLPR, HPTPA, HPTPalpha, LRP, PTPA, PTPRL2, R-PTP-alpha, RPTPA
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(5786) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(19262) protein tyrosine phosphatase, receptor type, A
  • Rat(25167) protein tyrosine phosphatase, receptor type, A
  • Zebrafish(140818) protein tyrosine phosphatase, receptor type, A
  • chicken(396060) protein tyrosine phosphatase, receptor type, A
  • domestic cat(101096558) protein tyrosine phosphatase, receptor type, A
  • Horse(100066880) protein tyrosine phosphatase, receptor type, A
  • dog(477176) protein tyrosine phosphatase, receptor type, A
  • sheep(101101909) protein tyrosine phosphatase, receptor type, A
  • cow(100138017) protein tyrosine phosphatase, receptor type, A
  • Domestic Rabbit(100342875) protein tyrosine phosphatase, receptor type, A
  • naked mole-rat(101716097) protein tyrosine phosphatase, receptor type, A
  • domestic guinea pig(100720460) protein tyrosine phosphatase, receptor type, A

Custom & Knockdown Gene Products

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-PTPRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-PTPRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
Anti-Phospho-PTPRA-Y789 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Milrinon, ≥97% (TLC), powder,
Spezies
rat, human

Proteins

Produktnummer
Beschreibung
Spezies
PTPRA (174-802), active, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human PTPRA, VPS16,
Spezies
human
MISSION® esiRNA, targeting mouse Ptpra,
Spezies
mouse