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Merck

SDHD

succinate dehydrogenase complex, subunit D, integral membrane protein

Synonyme:
CBT1, CII-4, CWS3, PGL, PGL1, QPs3, SDH4, cybS
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(6392) Summary: This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]
  • Mouse(66925) succinate dehydrogenase complex, subunit D, integral membrane protein
  • Rat(363061) succinate dehydrogenase complex, subunit D, integral membrane protein
  • naked mole-rat(101702014) succinate dehydrogenase complex, subunit D, integral membrane protein
  • domestic guinea pig(100734731) succinate dehydrogenase complex, subunit D, integral membrane protein
  • chicken(419793) succinate dehydrogenase complex, subunit D, integral membrane protein
  • cow(281481) succinate dehydrogenase complex, subunit D, integral membrane protein
  • domestic cat(101095280) succinate dehydrogenase complex, subunit D, integral membrane protein
  • dog(479438) succinate dehydrogenase complex, subunit D, integral membrane protein
  • sheep(101111485) succinate dehydrogenase complex, subunit D, integral membrane protein
  • Goat(100860881) succinate dehydrogenase complex, subunit D, integral membrane protein

Custom & Knockdown Gene Products

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-SDHD (CybS) Antibody, from rabbit, purified by affinity chromatography,
Speziesreaktivität
bovine, human, mouse, rhesus macaque, sheep
Anwendung
immunocytochemistry
western blot
Anti-SDHD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-SDHD Antibody, from rabbit, purified by affinity chromatography,
Speziesreaktivität
mouse
Anwendung
immunocytochemistry
western blot
Anti-SDHD antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunocytochemistry

immunofluorescence

western blot
Anti-SDHD/CybS Antibody, clone 1F5-H2L2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
bovine, goat, human, monkey, mouse, sheep
Anwendung
flow cytometry
immunocytochemistry

immunohistochemistry

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Sdhd,
Spezies
mouse
MISSION® esiRNA, targeting human SDHD,
Spezies
human