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SIAH1

siah E3 ubiquitin protein ligase 1

Synonyme:
SIAH1A
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(6477) Summary: This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]
  • dog(487293) siah E3 ubiquitin protein ligase 1
  • Zebrafish(80955) seven in absentia homolog 1 (Drosophila)
  • sheep(101111116) siah E3 ubiquitin protein ligase 1
  • domestic cat(101090311) siah E3 ubiquitin protein ligase 1
  • domestic guinea pig(100722988) siah E3 ubiquitin protein ligase 1
  • chicken(374076) seven in absentia homolog 1 (Drosophila)
  • naked mole-rat(101702094) siah E3 ubiquitin protein ligase 1
  • cow(534655) seven in absentia homolog 1 (Drosophila)

Custom & Knockdown Gene Products

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-SIAH1, (N-terminal) antibody produced in mouse, clone 2C5, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
Anti-SIAH1 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
western blot
Anti-SIAH1, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-SIAH1 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Speziesreaktivität
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Anwendung
immunohistochemistry
western blot
Anti-SIAH1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
canine, human, mouse, rat
Anwendung
ELISA
immunofluorescence

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human SIAH1, LONP2,
Spezies
human