TDG
thymine-DNA glycosylase
Synonyme:
hTDG
Spezies:
Human TDG (6996), Mouse Tdg (21665), Rat Tdg (114521), chicken TDG (395510), Zebrafish tdg (553789), sheep TDG (101123623), cow TDG (517825), Horse TDG (100053458), domestic cat TDG (101082502), dog TDG (475448) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(6996) Summary: The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]
- Mouse(21665) thymine DNA glycosylase
- Rat(114521) thymine-DNA glycosylase
- chicken(395510) thymine-DNA glycosylase
- Zebrafish(553789) thymine-DNA glycosylase
- sheep(101123623) thymine-DNA glycosylase
- cow(517825) thymine-DNA glycosylase
- Horse(100053458) thymine-DNA glycosylase
- domestic cat(101082502) thymine-DNA glycosylase
- dog(475448) thymine-DNA glycosylase
- naked mole-rat(101703457) thymine-DNA glycosylase
- domestic guinea pig(100724604) thymine-DNA glycosylase
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-TDG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
immunohistochemistry