TPCN2
two pore segment channel 2
Synonyme:
SHEP10, TPC2
Spezies:
Human TPCN2 (219931), Mouse Tpcn2 (233979), Rat Tpcn2 (309139), domestic guinea pig Tpcn2 (100729259), Zebrafish tpcn2 (777614), dog TPCN2 (483683), chicken TPCN2 (423141), cow TPCN2 (516679), naked mole-rat Tpcn2 (101712986), domestic cat TPCN2 (101086345)
UniProtKB-ID:
Gen-ID:
- Human(219931) Summary: This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.[provided by RefSeq, Dec 2009]
- Mouse(233979) two pore segment channel 2
- Rat(309139) two pore segment channel 2
- domestic guinea pig(100729259) two pore segment channel 2
- Zebrafish(777614) two pore segment channel 2
- dog(483683) two pore segment channel 2
- chicken(423141) two pore segment channel 2
- cow(516679) two pore segment channel 2
- naked mole-rat(101712986) two pore segment channel 2
- domestic cat(101086345) two pore segment channel 2
- sheep(101115493) two pore segment channel 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.