TTK
TTK protein kinase
Synonyme:
CT96, ESK, MPH1, MPS1, MPS1L1, PYT
Spezies:
Human TTK (7272), Mouse Ttk (22137), Rat Ttk (315852), Zebrafish ttk (317763), fruit fly ttk (48317), chicken TTK (421849), dog TTK (481895), Horse TTK (100069586), domestic cat TTK (101101566), sheep TTK (101113682) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(7272) Summary: This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
- Mouse(22137) Ttk protein kinase
- Rat(315852) Ttk protein kinase
- Zebrafish(317763) ttk protein kinase
- fruit fly(48317) tramtrack
- chicken(421849) TTK protein kinase
- dog(481895) TTK protein kinase
- Horse(100069586) TTK protein kinase
- domestic cat(101101566) TTK protein kinase
- sheep(101113682) TTK protein kinase
- cow(524925) TTK protein kinase
- Domestic Rabbit(100359213) TTK protein kinase
- domestic guinea pig(100723582) TTK protein kinase
- naked mole-rat(101702153) TTK protein kinase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.