805092

PLGA nanoparticles

100 nm average diameter

• Synonym(e): Degradex^® PLGA, poly(D,L-lactide-co-glycolide)
• Lineare Formel: HO(C₃H₄O₂)_x(C₂H₂O₂)_yH
• UNSPSC-Code: 12162002
• NACRES: NA.23

Eigenschaften

• Form: powder
• Qualitätsniveau: 100
• Durchschnittlicher Durchmesser: 100 nm
• Dichte: 1.3 g/cm³
• Versandbedingung: wet ice
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Degradex^® is made with poly(D,L-lactide-co-glycolide) with an L/G ratio of 50/50 and a Mw of 30,000.
To re-constitute:

• Remove the product from freezer.
• Wait until temperature rises to the ambient temperature.
• Add DI water or buffer to the container.
• Vortex and sonicate for 5 minutes to ensure the microspheres are well suspended.

The particle size of the PLGA nanoparticles are closely dependent on both the nature and concentration of the stabilizer and polymer.[1][2]

Anwendung

Plain PLGA particles can be used for testing system compatibility in drug delivery research. Particles can be used as carriers by attaching drug or biological/chemical entities to particle surface. PLGA particles are used for controlled release, sustained release and targeted drug delivery.A study reports the use of PLGA nanoparticles as estrogen carriers. The carrier-drug system was prepared by emulsification-diffusion method.[1][2]

Rechtliche Hinweise

Degradex is a registered trademark of Phosphorex, Inc.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable