BAD
BCL2-associated agonist of cell death
Synonyms:
BBC2, BCL2L8
Species:
Human BAD (572), Mouse Bad (12015), Rat Bad (64639), dog BAD (483763), domestic cat BAD (768269), sheep BAD (780444), cow BAD (615013), naked mole-rat Bad (101726042), domestic guinea pig Bad (100734151)
UniProtKB ID:
Gene ID:
- Human(572) Summary: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
- Mouse(12015) BCL2-associated agonist of cell death
- Rat(64639) BCL2-associated agonist of cell death
- dog(483763) BCL2-associated agonist of cell death
- domestic cat(768269) BCL2-associated agonist of cell death
- sheep(780444) BCL2-associated agonist of cell death
- cow(615013) BCL2-associated agonist of cell death
- naked mole-rat(101726042) BCL2-associated agonist of cell death
- domestic guinea pig(100734151) BCL2-associated agonist of cell death
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Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-rat BAD(S109) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
rat
Application
dot blot
Anti-phospho-rat BAD(S97) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
rat
Application
dot blot
Anti-Phospho-Bad-S112 antibody produced in rabbit, ,
Species Reactivity
human
Application
western blot
Anti-Phospho-Bad-S112 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-phospho BAD Antibody (Ser155), from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, canine, human, mouse, rat
Application
immunoprecipitation (IP)
inhibition assay
western blot
inhibition assay
western blot
Proteins
Product Number
Description
Species
BAD, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
esiRNA
Product Number
Description
Species