Skip to Content
Merck
HomeProductsChemistry & BiochemicalsChemical Building BlocksHalogenated Heterocycles

Halogenated Heterocycles

2-Bromo-3-pyridinecarboxaldehyde: halogenated pyridine for Suzuki coupling with an orthogonally reactive aldehyde group

Heterocyclic compounds are organic compounds that have at least one ring member that is not a carbon atom. Halogenated heterocyclic compounds have one or more halogen atoms (bromine, chlorine, fluorine, or iodine) attached. Halogenated heterocycles are significant because they are used as vehicles in the synthesis of other organic compounds in synthetic chemistry. Their structures can be modified in heterocyclic reactions to manipulate their function. Organo chlorine compounds are one of the most widely used groups for synthetic reactions. 

Natural heterocyclic compounds are essential in the metabolism of living cells. Heterocyclic bases, such as pyrimidine and purine, are inherent in DNA. In amino acids, the indole motif appears in tryptophan, while the pyrrolidine motif appears in proline. Many synthetic heterocycles exhibit pharmacological activity and are widely researched by medicinal chemists; others are used as ligands (i.e. NHCs) in pesticides, industrial antioxidants, copolymers, or various synthetic intermediates.  

Products

Sort by Relevance
Showing 1-20 of 2612
Change View
Showing 1-20 of 2612
Heptafluorobutyric acid
164194

Heptafluorobutyric acid

98%

Nonafluorobutane-1-sulfonic acid
562629

Nonafluorobutane-1-sulfonic acid

97%

Pentafluoropropionic acid
245917

Pentafluoropropionic acid

97%

4-Chloro-7-nitrobenzofurazan
163260

4-Chloro-7-nitrobenzofurazan

98%

2-Chloro-1-methylpyridinium iodide
198005

2-Chloro-1-methylpyridinium iodide

97%

4-Fluorobenzaldehyde
128376

4-Fluorobenzaldehyde

98%

Sodium trifluoromethanesulfonimide
762377

Sodium trifluoromethanesulfonimide

97%, powder

4-Fluoroaniline
F3800

4-Fluoroaniline

99%

Hexafluorobenzene
H8706

Hexafluorobenzene

99%

<I>O</I>-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride
194484

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride

≥98%

1-Fluoro-2,4-dinitrobenzene
42085

1-Fluoro-2,4-dinitrobenzene

purum p.a., ≥98.0% (GC)

2-Chloro-6-(trichloromethyl)pyridine
C1930

2-Chloro-6-(trichloromethyl)pyridine

≥98%

2-Bromopyridine
B80100

2-Bromopyridine

99%

Tetrafluoroterephthalonitrile
104426

Tetrafluoroterephthalonitrile

99%

2,3,4,5,6-Pentafluorobenzyl bromide
101052

2,3,4,5,6-Pentafluorobenzyl bromide

99%

1-Bromo-4-fluorobenzene
B67201

1-Bromo-4-fluorobenzene

99%

Iodonitrotetrazolium chloride
I10406

Iodonitrotetrazolium chloride

95%

4′-Fluoroacetophenone
F3207

4′-Fluoroacetophenone

99%

4-Fluorobenzoic acid
128384

4-Fluorobenzoic acid

98%

Pentafluoropropionic anhydride
252387

Pentafluoropropionic anhydride

99%

You have viewed 1-20 of 2612 results
Page 1 of 131
Page 1 of 131

Our diversified supply of over 3,000 halogenated heterocycles comprises our own core offering as well as that of partners’ compounds. We have the industry’s most comprehensive selection of heterocyclic building blocks that can be used in a vast array of synthetic protocols, including lithiation and palladium catalyzed cross-coupling methodologies.

Spark your scientific breakthroughs with our one-stop source for chemical reagents. Our portfolio of halogenated heterocycles includes:

  • organo fluorine heterocycles
  • organo chlorine heterocycles
  • organo bromine heterocycles
  • organo iodine heterocycles 
Related Product Categories
Fluorinated Building Blocks
With a vast offering of fluorinated building blocks, such as, trifluoromethyl, difluoromethyl, triflate, and pentafluorosulfanyl substituents for your toolkit, we make it even easier to discover your target compounds.
Heterocyclic Building Blocks
We’re proud to offer a comprehensive portfolio of heterocyclic building blocks, one of the largest and most diverse families of molecular fragments used in organic synthesis.
Organic Building Blocks
Find the basic components needed to drive your research forward in our portfolio of organic building blocks. Alkenesm alkanes, alkynes, arenes, allenes & more!
Related Applications
C–H Functionalization
C–H functionalization is the reliable and predictable conversion of a C–H into a C–C, C–N, C–O, or C–X bond in a selective and controlled fashion.
Cross-Coupling
Cross-coupling is a common reaction in organic chemistry for the creation of C-C, C-N, and C-O bonds with the aid of a metal catalyst.
Fluorination
Fluorination is the introduction of fluorine to a compound via electrophilic fluorination, nucleophilic fluorination, difluoromethylation, trifluoromethylation, or perfluoroalkylation.
Metathesis
Olefin metathesis involves an organic reaction that redistributes fragments of alkenes (olefins) by cleavage and transformation of carbon-carbon double bonds.
Organic Reaction Toolbox
An organic reaction toolbox provides structure-activity relationships for unique chemical reactions to optimally design and control small molecule synthesis.
Photocatalysis
Photoredox catalysis uses visible light and photocatalysts for synthetic transformations like cross-coupling and functionalization reactions.
Related Services
SYNTHIA™ Retrosynthesis Software
Our custom cell culture product design experts can offer advice and support as you scale your bioprocess from clinical to commercial supply, assisting with liquid products, dry powder products, selection of raw materials, quality testing, flexible product packaging, and product documentation.
Small Molecule Library Design
Aldrich Market Select offers online ordering of small molecule libraries and chemistry building blocks for compound management.
Sign In To Continue

To continue reading please sign in or create an account.

Don't Have An Account?