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  • [Synthesis of 2'-aminometylmorpholino nucleoside analogues containing 4'-carboxymethyl lynker group].

[Synthesis of 2'-aminometylmorpholino nucleoside analogues containing 4'-carboxymethyl lynker group].

Bioorganicheskaia khimiia (2012-04-14)
M F Kasakin, T V Abramova, V N Sil'nikov
ABSTRACT

A simple and effective method for the synthesis of 2'-aminomethylmorpholino-4'-carboxymethyl nucleoside analogues and Boc-modified derivatives as synthons for peptide synthesis was developed.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Morpholine, ReagentPlus®, ≥99%
Supelco
Morpholine, analytical standard
Sigma-Aldrich
Morpholine, purified by redistillation, ≥99.5%
Sigma-Aldrich
Morpholine, ACS reagent, ≥99.0%