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125660

Sigma-Aldrich

Leucomalachite Green

powder

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Synonym(s):
4,4′-Benzylidenebis(N,N-dimethylaniline)
Linear Formula:
C6H5CH[C6H4N(CH3)2]2
CAS Number:
Molecular Weight:
330.47
Beilstein:
2140506
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.47

form

powder

Quality Level

mp

100-102 °C (lit.)

λmax

623 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

CN(C)c1ccc(cc1)C(c2ccccc2)c3ccc(cc3)N(C)C

InChI

1S/C23H26N2/c1-24(2)21-14-10-19(11-15-21)23(18-8-6-5-7-9-18)20-12-16-22(17-13-20)25(3)4/h5-17,23H,1-4H3

InChI key

WZKXBGJNNCGHIC-UHFFFAOYSA-N

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Application

Leucomalachite green has been used as a reagent in presumptive tests which are used to detect invisible blood stains.

Biochem/physiol Actions

Leucomalachite green (LMG) is a chief metabolite of malachite green, a triphenylmethane dye that has been used generally as an antifungal drug in the fish industry. DNA adducts formed in livers of rats fed with leucomalachite green have been observed with little mutagenic or carcinogenic effect. LMG is one of the most commonly used reagents for presumptive blood test. It gives a characteristic green color in the presence of blood. LMG destroys DNA in the blood, therefore, the chances of DNA recovery and amplification is reduced or eliminated.

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Muta. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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